Immunology Experts Evaluate Causative Link Between Vaccination and Localized Fibrosing Disorder

Case Overview

This case involves a child who developed a rare disorder characterized by the formation of localized areas of fibrotic tissue, specifically in her left leg, which caused visual deformation of her leg and slightly impeded her movement. Before the disorder began to manifest itself, the child had received a number of vaccinations, including a combined vaccination against diphtheria, tetanus, and whooping cough. Some time later, the child also received another, different vaccination of Pediarix against diptheria, hepatitis B, pertussis, polio and tetanus. It was shortly after the child received this second vaccine that her father began to notice the formation of a small “knot” at the injection site of the vaccine, which continued to grow over time. It was alleged that the vaccinations caused the development of the localized fibrosing disorder.