This case involves a woman who required leg amputation after suffering from carbon monoxide poisoning. The woman was renting a house with a poor heating system and no fireplace. In early March, the woman’s heating system stopped working entirely. Her landlord gave her a propane space heater to warm up the house. One evening, the woman left the space heater on for many hours and lost consciousness. She was taken to the hospital the next day and discovered to have suffered carbon monoxide poisoning. She was discharged after 2 days. The woman was readmitted to the hospital a week later with severe foot and leg pain and circulatory disturbance. Over the course of the next few days, the woman developed rapidly progressive gangrene and high fever. The woman required a below the knee amputation.