This case involves a fifty-five-year-old male patient who underwent a holmium laser enucleation and total prostatectomy procedure and suffered many adverse complications. The patient complained of postoperative leg weakness, with the limited ability to ambulate. After the procedure, the patient continued to suffer from neurapraxia and rhabdomyolysis acutely that contributed to long-term leg weakness issues. The possibility of a nicked nerve during the radical resection procedure was not ruled out. Additionally, the patient underwent further independent medical examinations to uncover a source of the leg weakness.