This case involves a twenty-five-year-old female who was admitted to the hospital with a right femur shaft fracture. The woman was involved in a head-on collision, which caused her leg to be crushed in between her seat and the dashboard. She required orthopedic surgery to reset the fractured bone. The next day, the patient underwent successful intramedullary nailing for her injury. While in recovery, the woman experienced chest pain, shortness of breath, and an elevated heart rate. She told the nurse that she did not feel well. The woman also had a purple colored rash on her leg. The nurse increased the doses of her pain medications after discussing these findings with the orthopedic surgeon. The patient was not seen by the surgeon for another four hours, during which her symptoms became more pronounced. When the nurses checked on the woman during the night, she was unresponsive. Resuscitation was attempted, but she was confirmed to be in a coma, requiring life support. The woman was in a coma for one month, until her family decided to remove her from life support. It was later determined that she suffered a fat embolism, which was directly related to her fracture.